The Edit · Founder Insights
Your annual screening finds disease. Five other numbers predict the decline you can still prevent, and most Singaporeans have never had any of them tested.

Your annual health screening checks you for disease that might already be there. It does not measure how fast you are declining. Five other numbers do, and most Singaporeans have never had any of them tested. Together they predict your next twenty years of healthspan more accurately than your cholesterol panel.
TL;DR
- VO2 max. The strongest single predictor of all-cause mortality in modern medicine. The mortality risk of low fitness is comparable to or greater than that of smoking, diabetes, and hypertension.
- Grip strength. A 5 kg drop is associated with a 16% increase in all-cause mortality. The Asian Working Group sets the diagnostic floor at 28 kg for men and 18 kg for women, stricter than the European cutoffs.
- Visceral fat and waist-to-height ratio. What BMI cannot see. WHtR above 0.5 outperforms BMI as a metabolic risk marker, and Asians carry more visceral fat at lower BMI than Europeans do.
- Heart rate recovery. A drop of 12 bpm or fewer in the first minute after peak exercise doubles adjusted mortality risk, independent of every other cardiovascular variable.
- Skeletal Muscle Index. 32% of Singaporeans aged 60 and above already meet sarcopenia criteria. Most have no idea, because nobody has measured them.
What the standard executive package actually measures
A standard executive medical package in Singapore typically tests fasting blood glucose, a lipid panel, blood pressure, body mass index, a resting electrocardiogram, urinalysis, and on the fuller tiers a chest X-ray, a treadmill stress ECG, and a slate of tumour markers. The mid-range corporate packages run in the high hundreds of dollars; the comprehensive executive tiers, with imaging and a specialist review, push into the low thousands. The major providers each run their own versions of this. You can read the scope and inclusions directly on Raffles Medical and Parkway Shenton, both of which publish tiered packages from a basic blood-and-urine panel up to executive screens with cardiac imaging.
These packages are well constructed for what they were designed to do, which is to detect disease that is already present, or the biochemical early warning of it. A raised fasting glucose flags pre-diabetes. An abnormal lipid panel flags atherogenic risk. A resting or stress ECG flags an electrical or ischaemic problem with the heart. This is real, useful medicine, and you should keep doing it.
What the package does not measure is your functional capacity. It does not tell you how much oxygen your body can actually use under load, how strong you are, how much muscle you carry, or how quickly your nervous system recovers from exertion. It reads your biochemistry at rest. It does not read your physiology under stress, and physiology under stress is where the next twenty years of your healthspan is decided.
That gap is structural, not an oversight. The screening package was scoped for early disease detection at population scale, priced to be repeatable every year, and built around blood draws and a few standard machines. Functional testing needs a different setup, a different protocol, and a coach or clinician to administer it. It was never going to sit inside a blood-panel package, which is exactly why the five numbers below are missing from yours.
Why your screening misses these numbers
A diagnostic test asks one question: do you currently have a problem that needs treatment. A predictive test asks a different one: how is your trajectory over the next two decades, and what should you intervene on now to bend it. The five numbers below are predictive instruments. They are not replacements for your screening. They sit on top of it.
If your screening tells you whether the floor of your health is holding, these numbers tell you whether the ceiling is rising or falling. A 50-year-old can pass every line of a clean lipid panel and still be losing muscle, losing aerobic capacity, and carrying dangerous visceral fat that BMI cannot see. The screening will call that person well. The five numbers will not.
None of them require a referral. None of them are exotic. They are simply not in the package, because the package was scoped for early disease detection at population scale, not individual healthspan optimisation.
Number 1: VO2 max
VO2 max measures the maximum volume of oxygen your body can use per minute, scaled to body weight. It is the gold-standard read of cardiorespiratory fitness, and the cardiology literature has been remarkably consistent about its prognostic weight for forty years. I covered the testing options in Singapore, and why the true treadmill protocol is wrong for the people who most want it, in VO2 max test Singapore: what most clinics get wrong.
In 2018, Mandsager and colleagues at the Cleveland Clinic published one of the largest cohort studies ever conducted on this question, following 122,007 adults who completed a treadmill exercise test over a median 8.4 years of follow-up. Cardiorespiratory fitness was inversely associated with all-cause mortality with no observed upper limit of benefit, and the mortality risk of reduced fitness was comparable to or greater than traditional risk factors including smoking, diabetes, and hypertension (Mandsager et al., 2018).
Read that finding again. Higher cardiorespiratory fitness kept being more protective, all the way up, with no point at which more fitness stopped buying more life.
Your wearable does not measure VO2 max. It estimates one. Apple Watch, Garmin, and Whoop each infer it from heart-rate response to running pace, and the literature on their accuracy is mixed at best, with errors of plus or minus 10 to 15% common. Acceptable for tracking your own trend over time. Not acceptable as the input to a longevity decision. This is why we treat wearables as one input among many, integrated with structured testing rather than read in isolation, the approach we cover in the closed-loop recovery method.
The gold-standard read is a graded treadmill test with respiratory gas analysis taken to volitional exhaustion. That test is appropriate for athletes and adults who already train near maximum. For most people it is the wrong test, for two reasons. Running to true failure is not safe without prior conditioning, especially in the 45 to 60 demographic where cardiovascular risk is non-trivial. And people who have never been coached to recognise volitional failure quit early, producing a falsely low reading. Either way the test is wasted. The responsible read for the general population is a validated sub-maximal proxy. Catalyst uses the YMCA 3-minute step test on the 4-Pillar Healthspan Assessment, which estimates cardiorespiratory fitness from recovery heart rate against age- and sex-adjusted norms. The result lands on the Catalyst Healthspan Report as a band, from Excellent to Poor. It is honest information you can act on, with none of the risk of a maximal test attempted by someone who has not been built up for it. The free Healthspan Audit includes a self-report proxy that bands you against your peer group in three minutes before you ever set foot in the studio.
Number 2: Grip strength
Grip strength is a hand-dynamometer reading that takes 90 seconds. It is the most informative 90 seconds of medical data most adults will ever produce.
In the PURE study published in The Lancet in 2015, Leong and colleagues followed 139,691 adults across 17 countries. Each 5 kg reduction in grip strength was associated with a 16% increase in all-cause mortality and a 17% increase in cardiovascular mortality, after adjusting for age, sex, BMI, smoking, education, and physical activity level (Leong et al., 2015). The relationship held across high-income, middle-income, and low-income countries. It held in adults with and without pre-existing cardiovascular disease.
Why does a handheld test predict so much. The dynamometer reads systemic muscle quality at the periphery, and skeletal muscle is one of the most metabolically integrated organs in the body. Loss of grip is a downstream signal of mitochondrial decline, neuromuscular signal loss, protein-synthesis impairment, and chronic low-grade inflammation. It is a single number that aggregates many systems.
The Asian Working Group for Sarcopenia 2019 consensus update set the diagnostic cutoffs at 28 kg for men and 18 kg for women (Chen et al., 2020). These are tighter than the European Working Group cutoffs because Asian body composition differs and the threshold for clinically meaningful weakness sits at a different absolute number. I covered the broader picture in grip strength: the most underrated health metric.
Number 3: Visceral fat and waist-to-height ratio
Body mass index is a height-and-weight ratio. It does not know where the fat sits, and the location matters more than the total.
Visceral fat is the fat that sits inside the abdominal cavity, wrapped around organs. It is metabolically active in a way subcutaneous fat is not, secreting inflammatory cytokines that drive insulin resistance, hypertension, and atherogenic dyslipidaemia. Two adults with identical BMI can carry completely different visceral fat loads, and only one of them is at metabolic risk.
Waist-to-height ratio is a low-tech proxy that catches what BMI misses. Ashwell and colleagues in a 2012 systematic review and meta-analysis pooling 31 studies found WHtR consistently outperformed both BMI and waist circumference in identifying cardiometabolic risk across populations (Ashwell et al., 2012). The simple rule is: keep your waist circumference below half your height. A 175 cm man should be under 87.5 cm at the navel.
For Singaporeans this matters more than it does for Western populations. Asians carry a higher proportion of visceral fat at any given BMI than Caucasians do, which is part of why Singaporean adults can present with metabolic syndrome at BMI levels that would be considered normal in the United States or United Kingdom. The Health Promotion Board adopted lower BMI cutoffs (23.0 for elevated risk, 27.5 for high risk) for exactly this reason.
Catalyst measures WHtR on every assessment and pairs it with InBody segmental analysis to estimate visceral fat directly. I covered the practical relationship between SMI, WHtR, and longevity in body composition: SMI and waist-to-height ratio. For the deeper question of whether to choose InBody or DEXA when you want a precise visceral-fat measurement, the comparison is in DEXA vs InBody Singapore: which body composition test.
For the broader recomposition picture, the relationship between losing fat and holding muscle after 40 is covered in body recomposition after 40.
Number 4: Heart rate recovery
Heart rate recovery measures how quickly your heart rate drops in the minute after you stop exercising. The drop is driven by the parasympathetic branch of the autonomic nervous system, primarily through the vagus nerve.
In 1999, Cole and colleagues at the Cleveland Clinic published a study in the New England Journal of Medicine following 2,428 adults referred for treadmill testing. Adults whose heart rate dropped by 12 beats per minute or fewer in the first minute after peak exercise carried an adjusted relative risk of death of 2.0 over the following six years, after adjusting for age, sex, medications, cardiac risk factors, and exercise capacity (Cole et al., 1999). The unadjusted association is roughly four-fold; the figure that survives adjustment for every other variable is the doubling. Jouven and colleagues replicated the heart-rate-recovery mortality signal in 5,713 apparently healthy men in 2005, also in NEJM (Jouven et al., 2005). The signal is robust across populations and decades.
Your annual screening is designed to find disease. These five numbers are designed to predict decline.
What HRR captures is autonomic flexibility. A fast drop means your parasympathetic system can take the brakes off the sympathetic response and bring the body back to rest efficiently. A slow drop means that switch is sticky, which is correlated with chronic inflammation, insulin resistance, and elevated cardiovascular risk.
It is also one of the most trainable markers in the longevity panel. Eight to twelve weeks of structured strength training plus Zone 2 cardio produces measurable improvements in most adults. I went deeper on the difference between HRR and what your watch shows in heart rate recovery: what your watch can't measure.
Number 5: Skeletal Muscle Index
Skeletal Muscle Index is appendicular muscle mass divided by height squared, measured by bioimpedance (InBody) or DXA. It is the canonical input to a sarcopenia diagnosis.
The Asian Working Group for Sarcopenia 2019 consensus update set Asian-population thresholds at 7.0 kg/m² for men and 5.7 kg/m² for women on bioimpedance (Chen et al., 2020). Below those numbers, with low grip strength or slow gait speed, the formal diagnosis is sarcopenia. Above them, you may still be losing muscle at age-typical rates, just not at the threshold of disease yet. The full diagnostic workflow, including SARC-F, the 6-metre gait speed test, and the Singapore screening pathways, is in sarcopenia: the muscle-loss problem we are not talking about.
The local data is sobering. Pang and colleagues in the Yishun Study, published in JAMDA in 2021, found that 32.2% of Singaporeans aged 60 and above met AWGS sarcopenia criteria, rising further in the oldest age groups (Pang et al., 2021). Most of these adults have never had their muscle mass measured. They learn about sarcopenia after a fall, or a hip fracture, or a hospital admission for something else.
From your 30s, untrained adults lose roughly 1% of muscle mass per year. The trajectory accelerates after 60 if nothing intervenes. Structured strength training stops the loss, and in many cases reverses years of accumulated decline within twelve to sixteen weeks. The deeper read on muscle loss in the Singapore context is in sarcopenia: the muscle-loss problem we are not talking about.
The numbers a longevity coach acts on
A number is only useful if it changes what you do next. The whole reason these five sit outside the screening package is that they are actionable: every one of them maps to a specific intervention a coach can programme against and then re-measure. Here is what each one tells me to do.
A low VO2 max band tells me to build the aerobic base before anything else. That means Zone 2 cardio, the conversational-pace work that grows mitochondrial density and stroke volume, layered with short higher-intensity intervals once the base is in. The dose-response in the data has no ceiling, so for almost everyone the instruction is the same: add aerobic volume, then re-test the band in eight to twelve weeks. The honest first step for most people is the proxy in the free Healthspan Audit, which bands you before you commit to anything.
A weak grip and a low Skeletal Muscle Index tell me the same thing: load the body progressively. Grip and SMI are strength and muscle-mass numbers, and the only intervention that moves them is resistance training under progressive load, with enough protein to support synthesis. The programming detail differs by person, but the direction is fixed: heavier, structured, tracked. This is exactly the work covered in the minimum effective dose for real strength, and it is why lifting heavy does not make you bulky, it rebuilds the muscle the screening never told you was disappearing.
A high waist-to-height ratio tells me the lever is body composition, and that lever has two arms. Resistance training and aerobic work on the training side, and nutrition on the intake side, because visceral fat responds to a sustained calorie and protein strategy more than to any single session. WHtR is the cheapest of the five to re-measure: a tape at the navel, monthly. For members managing weight on a GLP-1 medication, holding muscle while the waist comes down is the entire game, which is why we built strength training on GLP-1 around protecting SMI through the cut; the muscle-loss mechanism itself is in GLP-1 weight loss and keeping your muscle.
A blunted heart rate recovery tells me the autonomic system needs both the training stimulus and the recovery structure around it. The fix is the same Zone 2 plus strength combination that moves VO2 max, plus attention to sleep and stress load, because HRR reads the nervous system, not just the heart muscle. It is one of the most trainable numbers in the panel, which makes it one of the most satisfying to re-measure. Across all five, the pattern is the same: a coach does not collect these numbers to file them. We collect them to set the next twelve weeks of programming and then prove the number moved.
Where this fits in your year
None of this is an argument against your annual checkup. The lipid panel, the fasting glucose, the blood pressure cuff, and the resting ECG are all useful instruments and you should keep doing them. They will tell you if something is wrong now. They will not tell you if your trajectory is wrong. For that, you need the five numbers above.
My recommendation to most members is straightforward: book the Catalyst Healthspan Assessment in the same week as your annual screening, ideally a day or two before. The data from VO2 max, grip strength, WHtR, HRR, and SMI gives your GP material to work with that the standard screening does not provide. A 50-year-old banking MD with a clean lipid panel but a treadmill VO2 in the 25th percentile and an SMI within a kilogram of the AWGS sarcopenia cutoff is not fine. He is on a slope. The screening cannot see the slope. The five numbers can.
If you want to see where you stand before booking anything, the Healthspan Audit is a free 12-question self-assessment that lands a banded score across all four pillars in your inbox in three minutes. It is the same framework, scaled to a self-report. The in-studio assessment replaces the proxies with real instruments, but the audit is a useful starting point if you want to know what you are walking into.
How this sits alongside Healthier SG and your GP screening
Most Singapore residents now have a national pathway for subsidised preventive care through Healthier SG, enrolled with a regular GP, alongside the age-based checks the Ministry of Health recommends from your 40s. That system is built to catch disease early, and it does that job well. What it was never scoped to measure is functional decline, which is where the five numbers above earn their place on top of it.
Cost rarely needs to be the barrier. Subsidised screening through Healthier SG is low-cost or free for eligible residents, and the fuller executive medical packages allow Medisave to be applied to approved components. The functional layer is the cheapest part to begin: the first 60-minute Catalyst Healthspan Assessment is complimentary and yours to keep, and you can start before you ever book by banding yourself across all four pillars in the free Healthspan Audit.
Some groups should pay particular attention. For women approaching or past menopause, bone and muscle loss accelerate sharply, and bone-density screening becomes a priority that standard packages often defer. Adults over 50 carry the steepest sarcopenia risk and benefit most from getting the functional numbers on record early, which is the focus of personal training over 50 in Singapore. If you are managing an injury or rebuilding after one, the functional baseline matters even more, and that work is covered in rehabilitation training.
Frequently asked questions
Q. Where can I get VO2 max measured in Singapore?
A true VO2 max test is a graded treadmill protocol taken to exhaustion with gas analysis, offered at sports-medicine clinics. For most adults it is the wrong test: running to failure is unsafe without conditioning, and the under-trained quit early and read falsely low. Catalyst uses the validated YMCA 3-minute step test on the 4-Pillar Healthspan Assessment. If you train near maximum, ask your GP for a sports-medicine referral with cardiology backup.
Q. Does a standard executive health screening already cover these five numbers?
No. The standard and even the comprehensive executive packages test biochemistry and resting cardiac function: fasting glucose, lipids, blood pressure, a resting or stress ECG, BMI, and imaging on the higher tiers. None of them measure VO2 max, grip strength, heart rate recovery, or skeletal muscle index, because those are functional tests that need a different setup. The screening reads your health at rest. The five numbers read your physiology under load, which is the part that predicts decline.
Q. Should I replace my annual checkup with a Catalyst assessment?
No. The Catalyst Healthspan Assessment does not test cholesterol, glucose, blood pressure, or resting ECG, and it is not a substitute for medical screening. It is an additional layer of data that sits alongside your screening, focused on the predictive markers the screening does not include. The two are complementary instruments, not competing ones. Keep your GP. Add the assessment.
Q. Does Healthier SG or Medisave cover any of this?
Healthier SG covers your subsidised disease-screening panel through your enrolled GP, and Medisave can be applied to approved components of the fuller medical packages. Neither currently covers functional testing like VO2 max, grip strength, or skeletal muscle index, because those sit outside the standard screening scope. The practical route is to keep your subsidised screening for the medical baseline and add the functional layer separately. The first Catalyst Healthspan Assessment is complimentary, so the starting cost there is nothing.
Citations
Mandsager, K., Harb, S., Cremer, P., Phelan, D., Nissen, S. E., & Jaber, W. (2018). Association of cardiorespiratory fitness with long-term mortality among adults undergoing exercise treadmill testing. JAMA Network Open, 1(6), e183605. jamanetwork.com
Leong, D. P., Teo, K. K., Rangarajan, S., et al. (2015). Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study. The Lancet, 386(9990), 266 to 273. thelancet.com
Ashwell, M., Gunn, P., & Gibson, S. (2012). Waist-to-height ratio is a better screening tool than waist circumference and BMI for adult cardiometabolic risk factors: systematic review and meta-analysis. Obesity Reviews, 13(3), 275 to 286. onlinelibrary.wiley.com
Cole, C. R., Blackstone, E. H., Pashkow, F. J., Snader, C. E., & Lauer, M. S. (1999). Heart-rate recovery immediately after exercise as a predictor of mortality. New England Journal of Medicine, 341(18), 1351 to 1357. nejm.org
Jouven, X., Empana, J. P., Schwartz, P. J., Desnos, M., Courbon, D., & Ducimetiere, P. (2005). Heart-rate profile during exercise as a predictor of sudden death. New England Journal of Medicine, 352(19), 1951 to 1958. nejm.org
Chen, L. K., Woo, J., Assantachai, P., et al. (2020). Asian Working Group for Sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment. Journal of the American Medical Directors Association, 21(3), 300 to 307.e2. jamda.com
Pang, B. W. J., Wee, S. L., Lau, L. K., et al. (2021). Prevalence and associated factors of sarcopenia in Singaporean adults: the Yishun Study. Journal of the American Medical Directors Association, 22(4), 885.e1 to 885.e10. jamda.com

