Quick answer
Do I need to train differently on GLP-1 medications like Ozempic or Wegovy?
Yes. GLP-1 receptor agonists cause meaningful lean mass loss when taken without concurrent resistance training. The body composition data from the STEP 1 trial (Wilding et al., 2021, NEJM) showed roughly 39% of total weight lost was lean mass in participants not engaged in concurrent resistance training. Catalyst Performance runs 1:1 personal training in Singapore CBD specifically calibrated for GLP-1 users: heavy resistance training to defend muscle, elevated protein targets to counter appetite suppression, and Skeletal Muscle Index re-tested at the 16-week Checkpoint against your baseline. Coordinated with your prescribing clinician.
